TRP channels are a group of membrane proteins that are expressed in various tissues and cells in the body. These channels are responsible for ion fluxes across the plasma membrane, which is essential for many cellular processes such as signal transduction, regulation of neuronal activity, and control of ion homeostasis. TRP channels are gated by various stimuli, including temperature, pressure, pH, and various chemical agents. Dysfunction of TRP channels has been linked to numerous medical conditions, such as chronic pain, neurodegenerative diseases, and cancer. Due to their crucial role in cellular physiology, TRP channels are emerging as therapeutic targets for various diseases and disorders.
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