What are the effects of hallucinogens on serotonin receptors?

Hallucinogens, such as LSD and psilocybin mushrooms, have a direct impact on serotonin receptors in the brain. These substances primarily target the serotonin 2A receptor subtype, leading to altered perception and cognition. When hallucinogens bind to these receptors, they modify the release and reuptake of serotonin, a neurotransmitter involved in mood regulation and various cognitive functions. The activation of serotonin receptors by hallucinogens can result in visual and auditory hallucinations, changes in thought patterns, and an altered sense of self and reality. Additionally, the interaction between these substances and serotonin receptors may contribute to long-lasting changes in brain connectivity and function, potentially playing a role in therapeutic applications for mental health disorders. Despite ongoing research, the exact mechanisms through which hallucinogens affect serotonin receptors are still being investigated.

This mind map was published on 5 December 2023 and has been viewed 43 times.