Which TRP channels are activated at different temperature ranges?

Transient receptor potential (TRP) channels are a diverse group of ion channels that play a crucial role in thermosensation. Several TRP channels are known to be activated at various temperature ranges. The TRPV1 channel is activated at temperatures above 43°C, whereas the TRPM8 channel is activated at temperatures below 26°C. The TRPV3 and TRPV4 channels are activated at temperatures between 30°C to 39°C and 27°C to 34°C, respectively. The TRPA1 channel is activated at lower temperatures below 17°C, making it an important player in sensing the cold sensation. Activation of TRP channels by temperature changes is essential for our ability to perceive different thermal stimuli and maintain homeostasis.

This mind map was published on 22 June 2023 and has been viewed 152 times.