Transient receptor potential (TRP) channels are cell membrane ion channels that play critical functions in regulating a wide range of physiological processes such as sensory transduction, cellular calcium signaling, and ion homeostasis. They are activated by various stimuli such as temperature, voltage changes, osmotic stress, and chemical ligands. The key functions of TRP channels include mediating pain and other sensory responses, controlling calcium signaling in cells, modulating smooth muscle contraction in the vasculature, and regulating immune function. TRP channels also play important roles in various diseases such as neuropathic pain, cancer, and inflammatory conditions, making them important therapeutic targets.
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