What are the consequences of central nervous system involvement in chronic pain?

When the central nervous system (CNS) becomes involved in chronic pain, it can have significant consequences. Firstly, there is often an increased sensitivity to pain due to neuronal changes within the CNS, amplifying the pain response. This hypersensitivity can result in the pain becoming more intense, lasting longer, and spreading to different areas of the body. Additionally, chronic pain can lead to changes in the structure and function of the CNS, such as shrinking of brain regions, altered connectivity, and impairments in cognitive processes. These alterations can contribute to a range of debilitating symptoms, including memory problems, difficulty concentrating, anxiety, and depression. Furthermore, the involvement of the CNS in chronic pain can create a vicious cycle where the pain itself changes the CNS, perpetuating and exacerbating the pain experience. Overall, the consequences of CNS involvement in chronic pain extend beyond the physical aspect, negatively impacting various domains of a person's life.
This mind map was published on 2 December 2023 and has been viewed 83 times.

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