How can TRP channels be targeted for cardiovascular therapies?

Transient receptor potential (TRP) channels play a significant role in cardiovascular physiology, including blood vessel regulation, cardiomyocyte function, and thrombosis. As such, targeting these channels represents an attractive therapeutic strategy for the treatment of cardiovascular diseases. The development of selective small molecule modulators or antibodies that target specific TRP channels could lead to novel treatment options for hypertension, heart failure, and arrhythmias. Additionally, targeting TRP channels in platelets could provide a means for preventing platelet aggregation and the formation of blood clots, a major contributor to heart attacks and strokes. Further research on the biology and pharmacology of TRP channels could lead to the development of new treatments for these common and serious cardiovascular diseases.

This mind map was published on 22 June 2023 and has been viewed 64 times.