What diseases are associated with TRP channel dysfunction in ion homeostasis?

Transient receptor potential (TRP) channels play a crucial role in regulating ion homeostasis in cells. Several diseases have been associated with TRP channel dysfunction related to ion homeostasis, which often results in abnormal cellular signaling and function. Diseases such as cystic fibrosis, polycystic kidney disease, hypertension, and irritable bowel syndrome have all been linked to TRP channel dysfunction. Additionally, recent evidence has identified TRP channels as potential therapeutic targets to treat these diseases, as well as other disorders associated with ion homeostasis.

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