What is the role of T3P?

T3P (tris(2-chloroethyl) phosphate) is a widely used reagent in organic synthesis, particularly in the field of peptide and amide synthesis. It serves as an efficient coupling reagent for the activation of carboxylic acids, which facilitates the formation of amide bonds with amines or other nucleophiles. T3P is a highly reactive and versatile reagent that has the ability to couple a wide range of substrates under mild reaction conditions, making it a valuable tool in chemical synthesis. Its key role lies in its ability to provide a fast and efficient route for amide formation without the use of harsh reagents or conditions.

This mind map was published on 16 May 2023 and has been viewed 114 times.