How do mutations in TRP channels affect sensory perception?

TRP channels are a group of ion channels that are involved in the perception of various sensory stimuli such as temperature, taste, and pain. Mutations in TRP channels can cause significant alterations in sensory perception. For example, mutations in the TRPV1 channel have been linked to altered temperature perception and increased sensitivity to pain, while mutations in the TRPM6 and TRPM7 channels can cause defects in touch and proprioception. Furthermore, mutations in other TRP channels such as TRPV4 and TRPA1 have been associated with various sensory disorders such as chronic pain and neuropathy. Overall, mutations in TRP channels can have profound effects on sensory perception and can lead to a range of sensory-related disorders.

This mind map was published on 22 June 2023 and has been viewed 131 times.