CTHRC1, or Collagen Triple Helix Repeat Containing 1, is a protein that plays a crucial role in various biological processes. It is primarily involved in tissue remodeling and wound healing. CTHRC1 regulates the extracellular matrix (ECM) and controls cell migration, proliferation, and differentiation. This protein is highly expressed during embryonic development and tissue repair, facilitating the reorganization of collagen fibers and promoting the formation of new blood vessels. Additionally, CTHRC1 has been implicated in cancer progression, as it promotes invasive behavior and metastasis by enhancing cell motility and ECM degradation. Understanding the function of CTHRC1 is vital for comprehending tissue repair and diseases associated with tissue remodeling, making it a promising target for therapeutic interventions.
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