How are TRPM6 and TRPM7 channels involved in magnesium homeostasis?

TRPM6 and TRPM7 channels are involved in maintaining magnesium homeostasis in the body. TRPM6 channel is present in the intestine and kidney, while TRPM7 channel is found in all cells of the body. TRPM6 channel is responsible for regulating intestinal absorption and renal reabsorption of magnesium. On the other hand, TRPM7 channel plays a crucial role in maintaining the intracellular magnesium concentration. It acts as a magnesium sensor and regulates magnesium uptake, storage, and release in cells. Any disruption in the function of these channels can lead to magnesium imbalance and related disorders such as hypomagnesemia or hypermagnesemia.

TRPM6 TRPM7 Magnesium Homeostasis Ion Channels Cellular Transport

How are TRPM6 and TRPM7 channels involved in magnesium homeostasis?

This mind map was published on 22 June 2023 and has been viewed 127 times.

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