What are the mechanisms of action of antiseizure drugs?

Antiseizure drugs, also known as antiepileptic drugs, work by modulating the activity of ions and neurotransmitters in the brain. They can enhance the inhibitory neurotransmitter gamma-aminobutyric acid (GABA) or decrease the activity of the excitatory neurotransmitter glutamate. Other mechanisms of action of antiseizure drugs include modulation of voltage-gated ion channels, inhibition of specific enzymes, and blocking of synaptic transmission. By affecting these mechanisms, antiseizure drugs can reduce the likelihood of seizures occurring or decrease the intensity of seizures when they do occur.

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