Can dysfunction of TRPV5 and TRPV6 channels lead to disease?
TRPV5 and TRPV6 channels are essential for calcium absorption and homeostasis. Dysfunction of these channels may lead to diseases such as osteoporosis, kidney stones, and hypocalcemia. Studies have shown that mutations in either TRPV5 or TRPV6 can lead to renal tubular disorder and decreased calcium absorption in the gut. Therefore, understanding the role of TRPV5 and TRPV6 in calcium regulation is crucial for preventing and treating calcium-related diseases.
This mind map was published on 22 June 2023 and has been viewed 70 times.
