What role does nitrofurantoin play in inhibiting fimbriae?

Nitrofurantoin is an antibiotic commonly used to treat urinary tract infections, and it works by inhibiting the synthesis of bacterial proteins and DNA. This antibiotic has also been found to play a role in inhibiting fimbriae, which are hair-like appendages on the surface of bacteria that help them attach to host cells and form biofilms. By inhibiting fimbriae, nitrofurantoin can prevent bacteria from effectively colonizing and infecting the urinary tract, making it a valuable tool in the treatment of urinary tract infections.

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