How will the mice be monitored for the onset of arthritis symptoms?

To monitor the onset of arthritis symptoms in mice, various techniques can be employed. Firstly, researchers often observe the mice for any visible signs of joint inflammation or swelling. They closely monitor changes in the mice's gait and movement patterns, looking for signs of limping or difficulty in mobility. Additionally, specialized instruments such as calipers can be used to measure the size of the mice's limbs and joints, as arthritis leads to swelling and enlargement. X-ray imaging is another effective method to assess the progression of arthritis in mice by identifying changes in bone density and joint damage. Furthermore, researchers can perform blood tests to measure specific biomarkers associated with arthritis. These biomarkers act as indicators of inflammation levels in the blood, providing insight into the onset and severity of arthritis symptoms. Monitoring the mice through a combination of visual observation, physical measurement, imaging, and blood tests allows researchers to accurately track and evaluate the development of arthritis symptoms in their preclinical studies.

This mind map was published on 12 December 2023 and has been viewed 94 times.