What are TRPV5 and TRPV6 channels?

TRPV5 and TRPV6 channels are calcium selective ion channels that control calcium absorption in the kidney and intestine respectively. These channels are members of the TRP (transient receptor potential) superfamily and are activated by changes in the extracellular calcium concentration. TRPV5 is highly expressed in the distal convoluted tubules of the kidney, where it regulates calcium reabsorption, while TRPV6 is found in the epithelium of the small intestine and plays a crucial role in dietary calcium absorption. Dysfunction of TRPV5 and TRPV6 channels can lead to calcium-related disorders such as osteoporosis and renal stone disease.

TRPV5 TRPV6 Ion Channels Calcium Transport Kidney Function

What are TRPV5 and TRPV6 channels?

This mind map was published on 22 June 2023 and has been viewed 60 times.

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