What are the physiological functions of TRP channels?

TRP channels are transmembrane ion channels that enable the transport of cations such as Ca2+, Na+ or Mg2+ across the cell membrane. The physiological functions of TRP channels are diverse, and include roles in pain sensation, thermoregulation, vision, vasodilation, taste and smell. In addition, TRP channels have been linked to numerous disease processes, such as diabetes, cardiovascular disease, neurodegeneration and various types of cancer. By modulating intracellular calcium levels and affecting the activity of downstream signaling pathways, TRP channels play a critical role in the physiological and pathophysiological responses of cells and tissues. As such, understanding the function of TRP channels is of significant interest for developing new therapies to target an array of diseases.

This mind map was published on 22 June 2023 and has been viewed 105 times.