What happens when TRPM6 and TRPM7 channels are dysfunctional?

TRPM6 and TRPM7 channels are essential for the regulation of magnesium and calcium levels in the body. Dysfunction of these channels can result in a range of health complications including hypocalcemia, hypomagnesemia, osteoporosis, and neuromuscular disorders. Symptoms may include muscle weakness, bone pain and fractures, abnormal heart rhythms, seizures, and mood disorders. In severe cases, dysfunction of these channels can lead to life-threatening conditions such as cardiac arrest. Early detection and surgical intervention may be necessary to prevent further complications.

This mind map was published on 22 June 2023 and has been viewed 59 times.